Can we delay the progression of type 1 diabetes?
Join Chantal Mathieu at The #LancetSummit (Nov 30-Dec 2, Sitges) to explore the latest advances in #T1D.
Register by Oct 31, 2026 using voucher code TLDC100 to save €100: spkl.io/60177VuVZ
The Lancet
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The Lancet
@TheLancet
Welcome to The Lancet, one of the world’s leading medical journals, published weekly since 1823.
thelancet.comIngressou em março de 2026
Presented at #ESMO2026 –
Izalontamab brengitecan versus platinum-based chemotherapy in EGFR-mutated advanced non-squamous non-small-cell lung cancer after progression on third-generation EGFR tyrosine kinase inhibitors (PANKU-Lung01): a multicentre, randomised, open-label, phase…
Presented at #ESMO2026 –
Ruzaltatug rezetecan versus chemotherapy for EGFR-mutated advanced non-small-cell lung cancer progressing after EGFR tyrosine kinase inhibitor therapy (HERON-Lung01): interim analysis of a randomised, open-label, phase 3 trial in China spkl.io/60187kgkn
Early-onset colorectal cancer (EO-CRC) is increasing globally.
In The Lancet Regional Health - Eastern Mediterranean, authors assessed the burden, temporal trends, and future projections of EO-CRC across the WHO Eastern Mediterranean Region: spkl.io/60147kJDg
Mitapivat, an oral pyruvate kinase activator, has the potential to be an effective and convenient disease-modifying treatment for people with sickle cell disease, finds study.
Explore the research: spkl.io/60107kyvi
Randomised controlled trials (RCTs) remain the most reliable method for controlling confounding and selection bias when evaluating interventions for clinical use.
A new Comment explores the need for more head-to-head RCTs comparing treatments already in common use: spkl.io/60147kyfy
Use of an AI chatbot ahead of GP appointments required no safety interventions in first real-world small study. However, authors caution that this study doesn't suggest AI chatbots are able to diagnose or triage patients without a doctor's oversight.
🔗 spkl.io/60117kysV
📣 Extended deadline: Nov 6
Still time to present your research: Submit abstracts on women’s cancers, haematological cancers, or cancer imaging to the #LancetSummit and help shape the future of #CancerControl in China and beyond: spkl.io/60157XLA3
In his latest Offline, Richard Horton reflects on discussions from the 2026 World Health Summit in Berlin, highlighting critical global health challenges.
Read more: spkl.io/60177kz2N
Presented today at #MSToronto2026: The REMODEL-1 and REMODEL-2 studies find that remibrutinib was superior to teriflunomide in patients with relapsing multiple sclerosis, while maintaining a favourable safety profile.
Explore the research: spkl.io/60137kz2B
Presenting at #ESMO2026—Izalontamab brengitecan for HR+/HER2– breast cancer in China (PANKU-Breast01): a randomised, phase 3 trial spkl.io/60157kJtJ @myESMO
The way digital technologies are built & governed creates real health risks worldwide.
In a new issue, a Series links digital media use to mental health & sleep problems plus reduced physical activity. Authors call for urgent, coordinated action.
Read this & more: spkl.io/60107ky5w
📢 Join our upcoming webinar!
Meet the editorial team of The Lancet Surgery & Anaesthesiology as they explore the journal's aims and scope and what they look for in a research paper.
👉 Register today: spkl.io/60147T2Cm #MedicalPublishing #LancetWebinar
Adding a hormonal coil during surgery for heavy menstrual bleeding reduces future hysterectomy risk by more than half, trial finds.
Find out more in The Lancet: spkl.io/60107Xx46
From trainee physician to CEO of @gavi, what can Dr Sania Nishtar's 30+ year career journey tell us about the future of global health?
Hear her unique insights at our International Health Lecture with @acmedsci🌎
📍 London
📅 Wed Nov 4, 2026
Register: spkl.io/60117VIhD
AI tool can predict cancer patients’ chances of survival from a single face photograph, study suggests.
Find out more in @LancetDigitalH: spkl.io/60167XBzr
Sierra Leone has a 1 in 52 lifetime risk of maternal death — adolescent girls face the greatest risk.
Join Cristina Fernandez Turienzo on 18 Nov to hear how 2YoungLives cut maternal & perinatal mortality by 48%.
👉 Register: spkl.io/60197pzPf
#GlobalHealth #EvidencetoImpact
Oral deucrictibant for on-demand treatment of hereditary angioedema attacks: a phase 3, multicentre, randomised, double-blind, placebo-controlled crossover trial spkl.io/60187XBc8
By 2050, almost 1 billion people are expected to live with osteoarthritis—a disabling musculoskeletal condition with currently no cure.
A new Health Policy outlines a roadmap for global health policy to prioritise, provide care, and prevent osteoarthritis: spkl.io/60107XBrj
GLP-1s associated with reduced need for acute psychiatric care for people with schizophrenia and type 2 diabetes, study of US data suggests.
Find out more in The Lancet Psychiatry: spkl.io/60197X6Uc
ICYMI—New antibody treatment reduces number of new abnormal bone lesions by at least 90% in people with ultra-rare genetic disorder, fibrodysplasia ossificans progressiva (FOP), phase 3 study shows.
Read now: spkl.io/60127X6rk
In our latest issue, a new Commission outlines 17 interlinked catastrophic threats to health & human survival between 2025 & 2100.
The report provides decision-makers with a common framework for coordinated action.
Read this & more: spkl.io/60117nhhU @IHME_UW…
📈 1 in 8 patients in African hospitals are critically ill — most don't get essential care.
Join Tim Baker on 18 Nov to hear how his team's Tanzania programme cut inpatient mortality by 31%.
👉 Register: spkl.io/60127pz32
#GlobalHealth #CriticalCare #EvidencetoImpact
Can we delay the progression of type 1 diabetes?
Join Chantal Mathieu at The #LancetSummit (Nov 30-Dec 2, Sitges) to explore the latest advances in #T1D.
Register by Oct 31, 2026 using voucher code TLDC100 to save €100: spkl.io/60137VupS
Hashimoto's thyroiditis is the most frequent autoimmune thyroid disease & the leading cause of hypothyroidism.
In @TheLancetEndo, a Review summarises developments over the past two decades and considers emerging approaches to precision medicine: spkl.io/60117nbZx
TRIUMPH-2 findings suggest that retatrutide might advance the treatment of people with obesity and type 2 diabetes, showing bodyweight reduction alongside improvements in glycaemic control and cardiometabolic risk factors. Read more: spkl.io/60147VfXi #EASD2026
What does it take to turn good research into lasting change? Ask the teams who've actually done it.
Join Maha Rhannam as she co-hosts our webinar with the inaugural Evidence to Impact Award winners.
👉 Register: spkl.io/60127pzzy
#GlobalHealth #EvidencetoImpact
ICYMI - Radiotherapy after surgery halves risk of recurrence in a type of brain tumour that can often grow back, trial shows.
Find out more in The Lancet: spkl.io/60147VN0i #EANO2026 @EANOassociation
🧠 Migraine is a chronic neurological disorder that affects over 1 billion people globally each year, with women predominantly affected.
A new Seminar discusses typical symptoms, mechanisms, and treatment options: spkl.io/60107VNQg
What will shape the health of the next generation?
A new Lancet Commission outlines 17 interlinked catastrophic threats to health and human survival between 2025 and 2100: spkl.io/60157nJvz #21stCenturyThreatsToHealth @IHME_UW @UNFPA
What will shape the health of the next generation?
A new Lancet Commission outlines 17 interlinked catastrophic threats to health and human survival between 2025 and 2100: spkl.io/60127VCtG #21stCenturyThreatsToHealth @IHME_UW @UNFPA
From trainee physician to CEO of @gavi, what can Dr Sania Nishtar's 30+ year career journey tell us about the future of global health?
Hear her unique insights at our International Health Lecture with @acmedsci🌎
📍 London
📅 Wed Nov 4, 2026
Register: spkl.io/60177VI7X
Use of an AI chatbot ahead of GP appointments required no safety interventions in first real-world small study. However, authors caution that this study doesn't suggest AI chatbots are able to diagnose or triage patients without a doctor's oversight.
🔗 spkl.io/60177VfXH
Substance use disorders are a major cause of disability, premature mortality & social harm worldwide.
A new study from The Lancet Regional Health Eastern Mediterranean looks at substance use disorder prevalence across 22 Arab League countries: spkl.io/60117VC8V
"Now, more than ever, medicine and public health leaders must challenge the zeitgeist of extreme populism and nationalism."
Richard Horton's latest Offline: Medicine for peace spkl.io/60167V414
Ahead of #WorldMentalHealthDay, our Editorial highlights the value of lived experience in mental health research and services, alongside critical challenges in its implementation.
Read now: spkl.io/60137V4GB
On the cover, a Review provides a series of roadmaps for advancing practice, research, and policy in the arts and health.
Read this & more: spkl.io/60127VNln
🆕 Out now: The Lancet Regional Health – Eastern Mediterranean’s inaugural issue. #goldopenaccess
“The scale of the challenges the region has faced this past year can be hard to absorb. It is in this context that this journal takes shape.”
Explore the new issue: spkl.io/60137VQID
Community need. Co-design. Sustainability. That's what it takes to turn evidence into impact.
Join Zoë Mullan, Editor-in-Chief of The Lancet Global Health, as she hosts our webinar with this year's Evidence to Impact Award winners.
👉 Register: spkl.io/60177pzJb
Can we delay the progression of type 1 diabetes?
Join Chantal Mathieu at The #LancetSummit (Nov 30-Dec 2, Sitges) to explore the latest advances in #T1D.
Register by Oct 31, 2026 using voucher code TLDC100 to save €100: spkl.io/60157Vurx
Three- and four-year-olds take over 18,500 steps a day on average, study suggests. However, step counts varied widely across participants.
Find out more in The Lancet Child & Adolescent Health: spkl.io/60127p2rq
One in eight cancers worldwide are linked to infections, global analysis estimates.
Find out more in @TheLancetOncol: spkl.io/60147p01y
Stereotactic body radiation therapy (SBRT) is the standard of care for early-stage, medically inoperable non-small-cell lung cancer (NSCLC).
A trial investigated the addition of neoadjuvant, concurrent, and adjuvant atezolizumab with SBRT: spkl.io/60177p0BW #ERSCongress @EuroRespSoc
In a new Clinical Rounds, authors present a case of neuroborreliosis in a man aged 59 years who initially complained of headache, tremor, and hiccups.
Find out more: spkl.io/60107p0He
Physiotherapist-led care for musculoskeletal conditions in the emergency department (RESHAP-ED): a randomised controlled trial with economic evaluation spkl.io/60127pLAk
"...because time is the last frontier of human experience that refuses to submit to our control, the future exerts a fascination and frustration that charms and defeats us in equal measure."
Richard Horton's latest Offline: spkl.io/60197pLf3