TheLancet
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TheLancet
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Welcome to The Lancet, one of the world’s leading medical journals, published weekly since 1823.
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thelancet.comIngressou em março de 2026
Hereditary haemolytic anaemias represent the most prevalent group of genetic disorders worldwide.
A Therapeutics paper provides a comprehensive overview of pyruvate kinase activators as a novel therapeutic approach for hereditary haemolytic anaemias: spkl.io/6019AFnYF
Richard Horton's latest Offline: The scandal of missing mothers spkl.io/6011AF7CT
On the cover, our latest Editorial—'Childhood cancer: progress, but not enough'
Read this & more in our latest issue ▶️ spkl.io/6011AF7IW
Information on childhood cancer burden is crucial for effective cancer policy planning.
A new #GBD study analysed the global burden of cancer in children and adolescents aged 0–19 years.
Explore the findings ➡️ spkl.io/6013AFniB @IHME_UW
📢 Have you registered?
👉 Register now: hubs.li/Q044__T00
There's still time to register to join The Lancet Medical Imaging & Theranostics team as they share top tips on how to prepare your manuscript for publication in their journal.
#MedicalPublishing #LancetWebinar
On April 16, join experts as they discuss a series of Cases in Global Social Medicine published in The Lancet.
The cases centre real clinical cases from around the world that together form a practical social medicine toolkit.
Register to attend: issi.berkeley.edu/centers/berkeley-center-...…
📣 Preliminary programme announced!
15 renowned academic and lived experience experts will lead an exceptional programme highlighting lessons learned in preventing #diabetes
View the programme and submit your abstracts by Jun 12: thelancetsummit.com/diabetes-prevention/su...…
Launched in 2025, Africa's new medicines regulator, the African Medicines Agency, is working to win the support of countries to meet its extensive agenda.
✍️ Andrew Green reports: spkl.io/6010AF95I
This year, UNGA will hold a follow-up #HLM on #pandemic prevention, preparedness, and response to review the implementation of the 2023 Political Declaration on PPPR2 and to consider IHR amendments and the landmark WHO #PandemicAgreement.
In @TheLancet, @avgfinch,
Peer reviewers are essential in upholding research integrity and scientific research standards.
We would like to express our thanks to the many dedicated peer reviewers who provided careful assessments and thoughtful comments on submissions to The Lancet in 2025. www.thelancet.com/journals/lancet/article/...
Retroperitoneal fibrosis is a rare immune-mediated disease which can be classified as idiopathic or secondary.
A new Seminar provides an overview of retroperitoneal fibrosis focusing on pathophysiology, differential diagnosis, and management: spkl.io/6010AFXEE
Africa produces less than 5% of the diagnostics and just 1% of the vaccines it uses — a dependency that weakens emergency response, increases costs, and puts lives at risk.
In our latest Correspondence in @TheLancet, co-authored with my colleagues at @AfricaCDC, we highlight the
🎙️ New Lancet Pulse – Prof Tien Yin Wong discusses Tsinghua’s world-first AI hospital project. Learn about the promise and reality checks of AI in healthcare, plus China’s broader health challenges. spkl.io/6015AFwRL
PCI before TAVI—necessary?
In patients with CAD, deferring PCI was noninferior to a PCI-first strategy at 1 year for the composite of death, MI, stroke, and major bleeding.
spkl.io/6018A0C78 #ACC26
Clopidogrel vs aspirin after PCI:
10-year HOST-EXAM follow-up shows lower ischemic and bleeding events with clopidogrel—but no difference in mortality.
Read more: spkl.io/6010A0hCy #ACC26
Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic cause of chronic kidney disease.
A Review focuses on current approaches to diagnosis, treatment, and specific aspects of clinical management. Read more: spkl.io/6013AF8kV
In 2023, there were over 250,000 deaths from meningitis globally, with over one third in children under five, suggests most comprehensive global assessment to date.
Find out more in @TheLancetNeuro: spkl.io/6014AF85j @IHME_UW
Sepsis is a serious condition where the body’s response to an infection becomes out of control and starts to damage its own organs.
A Seminar explores the complexity of the condition, and discusses current challenges and future developments in care: spkl.io/6011AFBJ3
Proton beam therapy for oropharyngeal cancer (TORPEdO): a phase 3, randomised controlled trial spkl.io/6017A0F8S
Primary sclerosing cholangitis is a rare liver disease, characterised by biliary inflammation and fibrosis.
A new Seminar explores the clinical features, pathogenesis, and challenges and opportunities in managing the disease: spkl.io/6017A0073
📣 Join our Lancet Webinar!
Join our expert editors as they guide you through the different pathways to publication for diabetes content across The Lancet Group and answer your questions about submitting your work to us.
Register now: hubs.li/Q046TzZF0
Alcohol-related liver disease could be nearly three times higher than previous estimates, new US study suggests.
Find out more in @LancetGastroHep: spkl.io/6017A0wzS
On #WorldTBDay, read a new comment by Charity Oga-Omenka & colleagues discussing how understanding where people with tuberculosis seek care can lead to better services and improved patient outcomes.
🔗 spkl.io/6010A0Ztq
🆕 A Profile captures the work and advocacy of Claire Calderwood, winner of the 2025 Stephen Lawn TB–HIV Research Leadership Prize: spkl.io/6017AL4ab @LSHTM_TB #WorldTBDay
Increased fluid intake is universally recommended to decrease the risk of recurrent urinary stones; yet, adherence is challenging.
🆕 A study investigated whether a behavioural intervention programme to promote high fluid intake reduces stone recurrence: spkl.io/6011A0P9b
🆕 Clinical Rounds: A multidisciplinary management approach to cervical cancer during pregnancy
Read now: spkl.io/6011ALI9Z
With the introduction of adaptive deep brain stimulation (aDBS) for Parkinson's disease, new questions emerge regarding who, why, and how to treat.
Find out more in a Therapeutics Review: spkl.io/6016ALFKk spkl.io/6015ALFKX
Survival outcome of VATS compared with open lobectomy for lung cancer: an individual patient data meta-analysis of randomised trials spkl.io/6016ALFjm
Oral semaglutide (a GLP-1 pill) is not effective at slowing progression in patients with mild Alzheimer's disease, find the EVOKE and EVOKE+ trials.
Find out more in The Lancet ▶️ spkl.io/6016ALITj
New Offline: Intelligence does not prevent stupidity spkl.io/6015ALFnW
GLP-1 receptor agonists have revolutionised obesity management. Yet high costs, limited production capacity, and supply-chain constraints have resulted in persistent inequitable access.
This could be about to change.
Find out more in our new issue: spkl.io/6014ALFHr
Sepsis is a serious condition where the body’s response to an infection becomes out of control and starts to damage its own organs.
A Seminar explores the complexity of the condition, and discusses current challenges and future developments in care: spkl.io/6015ALnw1
Hereditary haemolytic anaemias represent the most prevalent group of genetic disorders worldwide.
A new Therapeutics paper provides a comprehensive overview of pyruvate kinase activators as a novel therapeutic approach for hereditary haemolytic anaemias: spkl.io/6010ALnP8
📢 Have you reserved your space?
Join Pierre Nauleau for a Lancet Webinar exploring our new journal – The Lancet Medical Imaging & Theranostics. Get practical tips on how to optimise your manuscript for success.
👉 Register: hubs.li/Q044__qT0
Little evidence that cannabis products are effective treatments for mental health conditions, finds largest study to date.
Explore the research in The Lancet Psychiatry 👉 spkl.io/6019ALn1U
The April Issue of @TheLancetEndo is now online, featuring GLP-1 receptor agonists, healthy lifestyle, Cushing’s syndrome, automated insulin delivery, type 1 diabetes, Cushing’s disease, mental health, obesity, sleep, cardiometabolic health & much more www.thelancet.com/journals/landia/issue/cu...
Driven by high prices, lack of insurance, and a desire to lose weight, the rapid increase of fake and falsified obesity drugs is prompting public health concern.
✍️ Sophie Cousins reports: spkl.io/6014ALPKs
“Cancer world is an isolating place. For those of us who negotiate it while pregnant, the difficulties we encounter compound this feeling.”
Na'ama Carlin on cancer in pregnancy: navigating two medical systems
spkl.io/6014ALGLA
As the #Iran–#Israel–#US conflict escalates, we stand in solidarity with people in Iran & across Israel, the Middle East & Gulf.
Our editorial calls for a shift from country-first politics to a humanity-first approach.
tinyurl.com/2nc3z82e
Glaucoma is a leading cause of irreversible blindness worldwide and often goes undiagnosed until vision loss is advanced.
A new AI-based screening tool reduces the number of unnecessary referrals for glaucoma by half, according to a new study ▶️ spkl.io/6012AItOM
Sickle cell disease is a genetic red blood cell disorder, affecting nearly 8 million of people globally.
A new Seminar provides a comprehensive update & overview of the disease ▶️ spkl.io/6015AIsh1
Hormone therapy use and duration with postoperative radiotherapy for recurrent prostate cancer: an individual patient data meta-analysis
spkl.io/6018AIsQm
New Offline—The human consequences of Epic Fury spkl.io/6010AISsy
Sickle cell disease is one of the most prevalent and fastest-growing genetic disorders, affecting nearly 8 million people worldwide.
However, current global standards of care are not aligned with the scale and severity of the disease.
Read more in our Editorial▶️ t.co/KQtfAQUuGZ
On the cover of The Lancet: a call to enhance civilian and military blood preparedness.
With global demand already exceeding supply, establishing a clear preparedness timeline is vital.
Read more in our latest issue ▶️ spkl.io/6011AIUMB
“There’s more fraud around weight-loss injectables then I’ve seen at any other point during my career in tracking drug supply safety”
A new World Report on the boom in counterfeit obesity drugs: spkl.io/6010AIzJw
🩺 Enhance your clinical knowledge today through patient case studies, graphical summaries, & more.
Visit The Lancet’s Clinical Resources hub: spkl.io/6013AQYiV
In 2021, an estimated 6.3 million people were trafficked for sexual exploitation. Survivors experience profound sexual and reproductive health consequences—requiring more than clinical treatment.
Read more: spkl.io/6019AIK7x